Stem Cell Shape Regulates a Chondrogenic Versus Myogenic Fate Through Rac1 and N-Cadherin
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چکیده
منابع مشابه
Stem cell shape regulates a chondrogenic versus myogenic fate through Rac1 and N-cadherin.
Human mesenchymal stem cells (hMSCs) are multipotent cells that can differentiate into many cell types. Chondrogenesis is induced in hMSCs cultured as a micromass pellet to mimic cellular condensation during cartilage development, and exposed to transforming growth factor beta (TGFbeta). Interestingly, TGFbeta can also induce hMSC differentiation to smooth-muscle-like cell types, but it remains...
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ژورنال
عنوان ژورنال: STEM CELLS
سال: 2010
ISSN: 1066-5099,1549-4918
DOI: 10.1002/stem.308